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تقويمات 3 ع ت

تمرين حول فيروس كورونا

boudjendara ilias

06 فبراير 2022

التمرين الأول : فيروس كرورنا

في سنة 2019 ظهر في مدينة يوهان الصينية مرض كوفيد 19 ثم انتشر بسرعة في باقي دول العالم متسببا في الملايين من الاصابات والاف من الوفيات ، لعلاج كوفيد 19 استعملت بعض الادوية منها دواء الكلوروكين ، للتعرف على الية تأثيره نقترح الدراسة التالية :

الجزء الاول :

استعملت تراكيز ثابتة من انزيم غشائي TPMRSS 2 المتواجد ضمن ليزوزومات الخلايا الرئوية في محتوى هيولي مع تراكيز ثابتة من المستقبلات الغشائية ACE2 لنفس الخلايا الرئوية و ذلك في ودو وغياب مادة كلوروكين .

توضح المنحنيات الشكل (أ ) من الوثيقة (1) النتائج التجريبية المحصل عليها بينما يظهر الشكل ( ب) الية تثبيت فيروس كورونا على المستقبل الغشائي ACE2 في وجود انزيم TRMRSS2 حيث تعتبر المستقبلات الغشائية ACE2 المرتبطة بمحددات الفيروس كمادة تفاعل الانزيم TMPRSS2 المنشط للادماج :

بين تأثير الدواء الكلوروكين من خلال استغلالك لشكلي الوثيقة ( 1) .

الجزء ثاني : لتوضيح الية تأثير الدواء الكلوروكين على فيروس كورونا ، نقدم الوثيقة (2) التي تبين :

الشكل (أ) جدول ببين الشروط التجريبية ونتائجها وفي الوسطين المختلفين

الشكل (ب) : من نفس الوثيقة يمثل نمذجة التفاعل الانزيمي ( محددات الفيروس ACE2+ / TMPRSS2 ) . في درجات حموضة Ph مختلفة

اشرح الية تأثير دواء الكلوروكين باستغلال المعطيات الوثيق و (2 ) و معلوماتك .

تقويمات 3 ع ت

أخر المواضيع من قسم : تقويمات 3 ع ت

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\u0627\u0644\u0627\u0646\u0633\u0648\u0644\u064a\u0646 \u0648 \u0627\u0644\u063a\u0644\u064a\u0643\u0627\u063a\u0648\u0646 ', 'id': 5439428962118421477}, {'title': '\u0645\u062a\u0644\u0627\u0632\u0645\u0629 \u062f\u0627\u0648\u0646 trisomie 21 \u0648\u0627\u0635\u0627\u0628\u0629 \u0628\u0633\u0631\u0637\u0627\u0646 \u0627\u0644\u062b\u062f\u064a', 'id': 985466832780817259}, {'title': '\u062f\u0627\u0621 \u0627\u0644\u0633\u0643\u0631\u064a \u0627\u0644\u062a\u062c\u0631\u064a\u0628\u064a ( \u0643\u064a\u0641 \u064a\u062a\u0645 \u062a\u0646\u0637\u064a\u0645 \u0646\u0633\u0628\u0629 \u0627\u0644\u0633\u0643\u0631 \u0641\u064a \u0627\u0644\u062f\u0645 ) .', 'id': 4871831919522933692}]}, {'title': '\u0645\u0648\u0627\u0642\u0639 \u0627\u0644\u062a\u0648\u0627\u0635\u0644 \u0627\u0644\u0625\u062c\u062a\u0645\u0627\u0639\u064a', 'type': 'LinkList', 'sectionId': 'footer-social', 'id': 'LinkList2'}]}]); _WidgetManager._RegisterWidget('_PageListView', new _WidgetInfo('PageList1', 'pages', document.getElementById('PageList1'), {'title': '\u0627\u0644\u0635\u0641\u062d\u0627\u062a', 'links': [{'isCurrentPage': false, 'href': '/', 'title': '\u0627\u0644\u0635\u0641\u062d\u0629 \u0627\u0644\u0631\u0626\u064a\u0633\u064a\u0629'}, {'isCurrentPage': false, 'href': 'https://iliassnvdz.blogspot.com/p/blog-page_27.html', 'id': '5926135255542906879', 'title': '\u0645\u0646 \u0646\u062d\u0646'}, {'isCurrentPage': false, 'href': 'https://iliassnvdz.blogspot.com/p/blog-page_13.html', 'id': '8204780416770040671', 'title': '\u0633\u064a\u0627\u0633\u0629 \u0627\u0644\u062e\u0635\u0648\u0635\u064a\u0629'}, {'isCurrentPage': false, 'href': 'https://iliassnvdz.blogspot.com/p/blog-page_92.html', 'id': '5867645370275221626', 'title': '\u0634\u0631\u0648\u0637 \u0627\u0644\u0627\u0633\u062a\u062e\u062f\u0627\u0645'}, {'isCurrentPage': false, 'href': 'https://iliassnvdz.blogspot.com/p/blog-page_39.html', 'id': '1692255664585769846', 'title': '\u0627\u062a\u0635\u0644 \u0628\u0646\u0627 '}], 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'AddOns', document.getElementById('HTML2'), {}, 'displayModeFull')); _WidgetManager._RegisterWidget('_LabelView', new _WidgetInfo('Label3', 'Postcs5', document.getElementById('Label3'), {}, 'displayModeFull')); _WidgetManager._RegisterWidget('_LinkListView', new _WidgetInfo('LinkList4', 'sidepar', document.getElementById('LinkList4'), {}, 'displayModeFull')); _WidgetManager._RegisterWidget('_PopularPostsView', new _WidgetInfo('PopularPosts1', 'sidepar', document.getElementById('PopularPosts1'), {}, 'displayModeFull')); _WidgetManager._RegisterWidget('_LinkListView', new _WidgetInfo('LinkList2', 'footer-social', document.getElementById('LinkList2'), {}, 'displayModeFull'));